Chromophobe adenoma of the pituitary with Cushing's syndrome and skin pigmentation.

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Chromophobe adenoma of the pituitary with Cushing's syndrome and skin pigmentation.

A 76-year-old man with pigmentation and Cushing's disease is described, who was found to have a large chromophobe adenoma of the pituitary. Despite normal skull X-rays the presence of bitemporal hemianopia led to the diagnosis which was later confirmed at post-mortem. Adrenalectomy performed in the treatment of Cushing's disease may be followed by skin pigmentation and an enlarging pituitary tu...

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Cushing's syndrome and skin pigmentation.

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Background: The treatment of choice for Cushing’s disease is pituitary surgery. Second-line treatments include repeat pituitary surgery, radiation therapy, medical therapy, and bilateral adrenalectomy. The most used modalities to irradiate patients with Cushing’s disease include fractionated radiotherapy and single-dose Gamma Knife. We aim to review the efficacy and safety of radiotherapy in pa...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1979

ISSN: 0032-5473

DOI: 10.1136/pgmj.55.646.564